2025 March Madness round one complete odds: Lines, spreads for Round of 64

By Erich Richter
Published March 16, 2025, 10:23 p.m. ET
Cooper Flagg's availability is a major question going into the March Madness Tournament.
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It’s that time of year again.
The Selection Committee has made their choices – some bizarre ones at that – but complete odds are available for all of the first round of March Madness games.
First Four matchups begin Tuesday with Alabama State vs. Saint Francis (Pa.) at 6:40 p.m. ET.
It’s a big sports time ahead with March Madness taking us into baseball season and the NBA and NHL playoffs from there.
All odds are provided by FanDuel Sportsbook, which has a slew of profit boosts and free bet opportunities to wager on for both new and current users.
Auburn has slid a bit going into the first round of March Madness.
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2025 First Round March Madness odds
First Four odds
Alabama State vs. Saint Francis (Pa.)
Spread Moneyline Total
ALA -3.5 (-110) -162 Over 142.5 (-110)
FRAN +3.5 (-110) +134 Under 142.5 (-110)
North Carolina vs. San Diego State
Spread Moneyline Total
SDSU +3.5 (-118) +130 Over 142.5 (-110)
UNC -3.5 (-104) -156 Under 142.5 (-110)
Texas vs. Xavier
Spread Moneyline Total
TEX +2.5 (-110) +130 Over 142.5 (-110)
XAV -2.5 (-104) -156 Under 142.5 (-110)
San Diego State vs. North Carolina
Spread Moneyline Total
SDSU +3.5 (-118) +130 Over 142.5 (-110)
UNC -3.5 (-104) -156 Under 142.5 (-110)
Hunter Dickinson looks to continue strong March Madness play for Kansas.
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Hunter Dickinson looks to continue strong March Madness play for Kansas.
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Arkansas vs. Kansas
Spread Moneyline Total
ARK +5.5 (-114) +176 Over 146.5 (-110)
KAN -5.5 (-106) -215 Under 146.5 (-110)
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Round of 64 odds
Gonzaga vs. Georgia
Spread Moneyline Total
GA +6.5 (-110) +130 Over 142.5 (-110)
GON -3.5 (-104) -156 Under 142.5 (-110)
Utah State vs. UCLA
Spread Moneyline Total
UTAH ST +5.5 (-118) +172 Over 143.5 (-114)
UCLA -5.5 (-104) -210 Under 143.5 (-106)
VCU vs. BYU
Spread Moneyline Total
VCU +2.5 (-110) +122 Over 143.5 (-110)
BYU -2.5 (-110) -146 Under 143.5 (-110)
Creighton vs. Louisville
Spread Moneyline Total
CRE +2.5 (-118) +108 Over 145.5 (-108)
LOU -2.5 (-104) -130 Under 145.5 (-112)
UNC Wilmington vs. Texas Tech
Spread Moneyline Total
UNC W +15.5 (-102) +1060 Over 141.5 (-110)
TTU -15.5 (-118) -2300 Under 141.5 (-110)
St. Johns comes in as a No. 1 seed in the NCAA March Madness Tournament.
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St. Johns comes in as a No. 2 seed in the NCAA March Madness Tournament.
JASON SZENES FOR THE NEW YORK POST
Omaha vs. St. Johns
Spread Moneyline Total
OMAHA +17.5 (-102) +1280 Over 146.5 (-115)
ST. JOHNS -17.5 (-120) -3000 Under 146.5 (-105)
Wofford vs. Tenneesee
Spread Moneyline Total
WOFF +19.5 (-110) +1600 Over 132.5 (-110)
TENN -19.5 (-110) -4500 Under 132.5 (-110)
Yale vs. Texas A&M
Spread Moneyline Total
YALE +7.5 (-114) +250 Over 142.5 (-110)
A&M -7.5 (-106) -156 Under 142.5 (-110)
High Point vs.Purdue
Spread Moneyline Total
HIGH +9.5 (-118) +320 Over 154.5 (-105)
PUR -9.5 (-104) -420 Under 154.5 (-115)
McNeese vs. Clemson
Spread Moneyline Total
MCN +7.5 (-105) +275 Over 134.5 (-110)
CLEM -7.5 (-115) -350 Under 134.5 (-110)
SIU Edwardsville vs. Houston
Spread Moneyline Total
SIU +28.5 (-110) 65/1 Over 126.5 (-110)
HOU -328.5 (-110) -100000 Under 126.5 (-110)
Montana vs. Wisconsin
Spread Moneyline Total
MONT +16.5 (-102) +1160 Over 148.5 (-115)
WISC -16.5 (-120) -2800 Under 1428.5 (-105)
Drake vs. Missouri
Spread Moneyline Total
DRA +6.5 (-105) +230 Over 133.5 (-110)
UNC -6.5 (-115) -285 Under 133.5 (-110)
UC San Diego vs. Michigan
Spread Moneyline Total
UCSD +2.5 (-102) +126 Over 141.5 (-110)
MICH -2.5 (-120) -152 Under 141.5 (-110)
Lipscomb vs. Iowa State
Spread Moneyline Total
LIPS +13.5 (-106) +750 Over 143.5 (-106)
IOST -13.5 (-114) -1250 Under 143.5 (-114)
New Mexico State vs. Marquette
Spread Moneyline Total
NMS +3.5 (-110) +138 Over 152.5 (-110)
MARQ -3.5 (-110) -166 Under 152.5 (-110)
Baylor vs. Mississippi State
Spread Moneyline Total
BAY -1.5 (-102) -114 Over 142.5 (-106)
UNC +1.5 (-120) -105 Under 142.5 (-114)
Robert Morris vs. Alabama
Spread Moneyline Total
ROB +22.5 (-110) +2000 Over 165.5 (-115)
ALA -22.5 (-110) -7000 Under 166.5 (-105)
Grand Canyon vs. Maryland
Spread Moneyline Total
GC +22.5 (-120) +460 Over 150.5 (-110)
MARY -22.5 (-102) -650 Under 150.5 (-110)
Liberty vs. Oregon
Spread Moneyline Total
LIB +6.5 (-110) +220 Over 140.5 (-115)
ORE -6.5 (-110) -275 Under 140.5 (-105)
Colorado St. vs. Memphis
Spread Moneyline Total
CO St. +2.5 (-105) -134 Over 145.5 (-110)
MEM -2.5 (-115) +112 Under 145.5 (-110)
Bryant vs. Michigan State
Spread Moneyline Total
BRY +17.5 (-102) +1280 Over 150.5 (-115)
MSU -17.5 (-120) -3500 Under 150.5 (-105)
Vanderbilt vs. Saint Mary’s
Spread Moneyline Total
VAN +4.5 (-110) +158 Over 136.5 (-110)
MAR -4.5 (-110) -192 Under 136.5 (-110)
Norfolk St. vs. Florida
Spread Moneyline Total
NOR St. +27.5 (-102) +5000 Over 153.5 (-110)
UNC -27.5 (-120) -30000 Under 153.5 (-110)
Dan Hurley comes in as a favorite against Oklahoma in the first round.
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Dan Hurley comes in as a favorite against Oklahoma in the first round.
IMAGN IMAGES via Reuters Connect
Oklahoma vs. UConn
Spread Moneyline Total
OKL +4.5 (-110) +158 Over 146.5 (-110)
UCONN -4.5 (-110) -194 Under 146.5 (-110)
Akron vs. Arizona
Spread Moneyline Total
AK +13.5 (-118) +610 Over 166.5 (-110)
ARI -13.5 (-104) -950 Under 166.5 (-110)
Troy vs. Kentucky
Spread Moneyline Total
TROY +10.5 (-102) +460 Over 152.5 (-114)
KEN -10.5 (-120) -650 Under 162.5 (-106)
Why Trust New York Post Betting
Erich Richter is a brazilian jiu-jitsu blue belt but he has a black belt in MMA betting. During the football season he’s showcased massive profits at The Post in the player prop market the last two seasons. While constantly betting long shots, his return on investment is 30.15 percent since 2022.
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