Knicks vs. Pistons series odds, picks, preview

By Dylan Svoboda
New York Knicks guard Jalen Brunson #11, speaking to the media after practice at the Knicks practice facility in Tarrytown, New York.
Jalen Brunson and the Knicks open against the Pistons in the 2025 playoffs.
Charles Wenzelberg / New York Post
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The New York Knicks are massive favorites over the upstart Detroit Pistons in Round 1 of the 2025 NBA playoffs.
The Knicks currently sit at -380 to win the series, the second-biggest favorite among the non-No. 1 seeds.
Detroit came out of nowhere to win 44 games this season, but it’s far from a fluke, and it may signal that the Knicks will have a bit more trouble than oddsmakers are expecting.
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Knicks vs. Pistons series betting odds
Team Odds
Knicks -380
Pistons +300
Odds via bet365
Knicks vs. Pistons betting preview
The Pistons handled this matchup during the regular season, going 3-1 in four contests, although injuries played a major role for the Knicks in those games.
Detroit’s star player, Cade Cunningham, dominated the Knicks during the regular season, averaging 30.8 points on 56.3 percent shooting and 52 percent from 3, with five rebounds and 8.3 assists.
New York Knicks guard Miles McBride (2) defends against Detroit Pistons guard Cade Cunningham (2) during the second half at Little Caesars Arena.
New York Knicks guard Miles McBride (2) defends against Detroit Pistons guard Cade Cunningham (2) during the second half at Little Caesars Arena.
IMAGN IMAGES via Reuters Connect
The Knicks’ opponent can be mistaken for a young team, but the Pistons’ roster is actually riddled with veteran talent that includes Tobias Harris, Dennis Schroder, Malik Beasley, and Tim Hardaway Jr., who surround Cunningham with some playoff know-how.
These rosters just aren’t close to the same, though.
Aside from Cunningham, the Knicks’ entire starting lineup would be a welcome addition to Detroit’s.
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Knicks vs. Pistons pick
There is something special about the Pistons, with their star player leading the way with a supporting cast of misfits, which I think will keep this series closer than expected.
But don’t bet on the Knicks to get off easy.
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The Play: Knicks-Pistons Over 5.5 games (-125, bet365)
Why Trust New York Post Betting
Dylan Svoboda is a versatile writer and analyst across many sports. He’s particularly knowledgeable about the big three — MLB, the NFL and the NBA.
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